ALLETHRIN Toxbase summary Toxicity Dermal and inhalational exposures are . “supernormal period” is the period for which the action potential induced by a. They are not considered to cause delayed neurotoxicity of the kind induced by some organophosphorus compounds. The mechanism of toxicity of synthetic. Allethrin had 96 h LC50 toxicity values of µg/L, µg/L > µg/L, and .. is followed by induction of microsomal oxidase activity (Škrinjarič-Špoljar et al.

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Quantitative determination of serum triglycerides by the use of enzymes.

Allethrin toxicity causes reproductive dysfunction in male rats. – Semantic Scholar

Here, we stained the respiratory and hepatic tissue only with hematoxiline-eosin, though other staining technique such as DAPI staining could be done to observe apoptotic cells more precisely. By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy PolicyTerms of Serviceand Dataset License.

The exposure of MC smoke resulted dose dependent depletion of BUN and total protein activity in all inhaled animals. Toxicological effects of MC smoke on hepatic tissue in control and smoke inhaled mice are shown in Fig. Additional evidence has also confirmed the involvement of neutrophil in the degradation of elastin fibers with subsequent development of emphysema [ 32 ]. Inflammatory response, reactive oxygen species, programmed necrotic-like and apoptotic cell death and cancer. The neurotoxicity of organochlorine and pyrethroid pesticides.

Habibur Rahman2 K. By the end of treatment period, blood sample was drawn from each mouse and blood biochemical parameters including alanine transaminase ALTaspartate transaminase ASTblood urea nitrogen BUNserum total protein, cholesterol, low density lipoprotein LDL and triglyceride TG were analyzed.

The authors have declared that they have no competing interests. Upon burning, MC emits smokes, containing single or multiple insecticides, which creates a defending environment and protects the subject from several mosquito borne lethal diseases including malaria, filaria and dengue. On the other hand pyrethroids have well been reported to induce oxidative stress and alter antioxidant level in different organ systems of rodent animal [ 23 ].


Mosquito coil, used in this study was purchased from local super market of Rajshahi by the trade name of Mortein power booster coil from Reckitt Benckiser, Bangladesh Ltd. Pulmonary tissue of inhaled mice illustrates various degrees of histo-architectural changes in a doses dependent manner in comparison with that of control Fig.

Poly ADP ribose polymerase. Effect of immunization against prostate- and testis-expressed PATE proteins on sperm function and fecundity in the rat.

Airway collagen and elastic fiber content correlates with lung function in equine heaves. Elastolytic metalloproteinases produced by human mononuclear phagocytes. Smoke inhalation injury in sheep is caused by the particle phase not the gas phase. However, the use of MC is increasing day by day in third world countries in particular but, yet to receive enough attention of both policy maker and general public.

Hogg JC, Timens W. References Publications referenced by this paper. In this study, we could not check the function of respiratory system such as X-ray analysis respiratory system due to lack of proper facilities.

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However, it is the first study that documented the raised cholesterol level in rodent animal treated with allethin based MC smoke via inhalation. Toicity ROS, induced by MC smoke, interferes with the antioxidant defense system [ 16 ], which would triggers inflammatory response in damage sites [ 30 ]. Toxicological effects of inhaled mosquito coil smoke on the rat spleen: Further, its effects on the male reproductive tract remain uncharacterized.

Toxicological effects of prolonged and intense use of mosquito coil emission in rats and its implications on malaria control. Potential roles in destructive lung disease. Forty days old mice were randomly distributed into control and inhaled group: The active ingredient of this brand was 0.


Prallethrin induced biochemical changes in erythrocyte membrane and red cell osmotic haemolysis in human volunteers. However, the recruited inflammatory cells along with proteolytic enzymes act upon the anti-proteases collagen and elastin in alveolar region and inactivate them which in turn results in the destruction of alveolar septa and eventually develop emphysema [ 29 ].

Provided statistical and methodological support as well as revised the manuscript.

Histological study Histological study was carried out using the protocol previously described by Carleton et al. Ataur Rahman2 M. A toxxicity method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.

Pyrethroids and Pyrethrins are the main active ingredients of MC. Hypersensitivity pneumonitis due to residential mosquito-coil smoke exposure. It implies that air ventilation through the bronchi and bronchiole in treated mice might be considerably reduced due to constricted bronchi CB in Fig. Endocrine disrupting potential and reproductive dysfunction in male mice exposed to deltamethrin. Elevated transaminase level has also been reported previously by Karthikeyan et al. Enantioselective disruption of the endocrine system by Cis-Bifenthrin in the male mice.

Transcription and post-transcriptional regulation of spermatogenesis. The datasets, supporting the conclusions of the inruced of this study are included within the article. Accumulation of inflammatory cells probably induces deposition of extracellular matrix in the sub epithelium region and contributes in thickening of bronchial epithelial wall [ 37 ]. In this study, we found the biochemical and histological effects of the mosquito coil smoke using mice model.