Apical periodontitis (AP) is an inflammatory lesion of the periradicular tissues caused by micro-organisms or their by-products (Kakehashi et al. ( Kakehashi. Author: Kakehashi et al. Year: Journal: OOO. Aim. -‐ To observe the pathologic changes resulting from untreated experimental pulp exposures in germ-‐. Kakehashi, S., Stanley, H.R. and Fitzgerald, R.J. () The effects of surgical exposures of dental pulps in germfree and conventional laboratory rats.

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Anatomy of the Pulp Space. Correlation between Sensibility Testing and Histology.

Culturing Techniques and Effects on Prognosis. Methods and Criteria in the Evaluation of the Biological Effects. Diagnosis and Treatment of Endodontics Flare-ups.

THE EFFECTS OF SURGICAL EXPOSURES OF DENTAL PULPS IN GERM-FREE AND CONVENTIONAL LABORATORY RATS.

Histology and Physiology at the Peri-apex. Histology of the Pulp Space. Interaction of Pulpal Health and Systemic Diseases. Microflora of the Peri-apex. Microflora of the Pulp. Odontogenic vs Non-Odontogenic pain. Related Factors and Kakehawhi.

Response of the Pulp to Caries. Response of the Pulp: Restoration of Endodontically Treated Teeth. Biocompatibility of various dental materials: Int J Periodontics Restorative Dent 16 3: To test the influence of bacteria on surgically exposed dental pulps.

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Both were fed sterile food. The animals were anesthetized and a carbide bur was used to drill a hole through the occlusal of enamel and dentine of the maxillary right first molar to expose pulpal tissue. In many cases, perforations laterally or apically occurred and no attempts were made to restore these perforations causing food and debris to become packed into the pulpal tissues.

THE EFFECTS OF SURGICAL EXPOSURES OF DENTAL PULPS IN GERM-FREE AND CONVENTIONAL LABORATORY RATS.

The animals were sacrificed at intervals from 1 to 42 days and a block resection was done and fixed and stained and evaluated. In the conventional animals, samples from the 8th day showed vital pulp tissue only in the apical half of the roots with the coronal portion necrotic and purulent and bacteria present.

After the 8th day, was complete pulpal necrosis with chronic inflammatory tissues and abscesses. No pulpal repair tissue was evident in any of the samples. In the germ-free animals, no completely devitalized pulp was found in any of the animals.

Pulpal inflammation was minimal in every sample and no apical abscesses were found. Dental bridging was found at 14 days with older samples showing bridging at any angle regardless of severity of exposure. The presence or absence of bacteria is a major factor in healing of exposed rat pulps. Link to Full Article. Comments, questions, problems, or feedback. Kakehasbi Anatomy of the Pulp Space Bleaching: Related Factors and Prevention Pulp Physiology 1: Blood Supply Pulp Physiology 2: Dental Materials Response of the Pulp: Oral Surg Oral Med oral Path 20 3: Aim To test the influence of bacteria kakehaashi surgically exposed dental pulps.

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The animals were anesthetized and a carbide bur was used to drill a hole through the occlusal of enamel and dentine of the maxillary right first molar to expose pulpal tissue In many cases, perforations laterally or apically occurred and no attempts were made to restore these perforations causing food and debris to become packed into the pulpal tissues.

Results In the conventional animals, samples from the 8th day showed vital pulp tissue only in the apical half of the roots with the coronal portion necrotic and purulent and bacteria present. Conclusion The presence or absence of bacteria is a major factor in healing of exposed rat pulps.